Veille d’hiver (publication en avril), couvrant les mois de janvier, février et mars .
Veille d’hiver (publication en avril), couvrant les mois de janvier, février et mars.
Néonatalogie
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The Effect of Oropharyngeal Colostrum Administration on Early Feeding Skills and Transition to Oral Feeding in Preterm Infants: A Randomized Controlled Trial
Adv Neonatal Care. 2026 Apr 9. doi: 10.1097/ANC.0000000000001351. Online ahead of print.ABSTRACTBACKGROUND: Failure to meet cue-based feeding and delay in developing oral feeding skills may cause long-term problems for premature infants.PURPOSE: The aim of this study was to determine the effects of oropharyngeal colostrum administration to premature infants on readiness …
Cue-based feeding and growth in preterm infants: a two-year follow-up study
Front Pediatr. 2026 Mar 25;14:1771033. doi: 10.3389/fped.2026.1771033. eCollection 2026.ABSTRACTAIM: To study the association between cue-based feeding (CBF) and growth trajectories and feeding characteristics up to two years of age.METHODS: A retrospective cohort study of preterm infants born at 27⁰/₇-33⁶/₇ weeks' gestation across two feeding epochs [traditional feeding (TF) vs. CBF]. Anthropometric …
Multi-directional phototherapy vs. unidirectional phototherapy from below for severe neonatal jaundice: a randomized pilot trial in home phototherapy
Eur J Pediatr. 2026 Apr 14;185(5):260. doi: 10.1007/s00431-026-06924-4.ABSTRACTSevere neonatal jaundice is a common problem, carrying a risk of neurologic toxicity. Phototherapy has become the standard treatment for jaundiced infants, eliminating the need for exchange transfusion and the risk of neurotoxicity. We hypothesized that treatment with multi-directional phototherapy would …
Zinc supplementation for prevention of neonatal hyperbilirubinemia: A systematic review and meta-analysis
J Neonatal Perinatal Med. 2026 Apr 17:19345798261443967. doi: 10.1177/19345798261443967. Online ahead of print.ABSTRACTGiven the potential of enteral zinc to reduce enterohepatic circulation of unconjugated bilirubin, we aimed to synthesize evidence from randomized controlled trials (RCTs) on zinc supplementation for prevention of neonatal hyperbilirubinemia (NNH). We searched PubMed, Embase, Scopus, and CENTRAL for …
Cord Bilirubin and 24-Hour Serum Bilirubin as Predictors of Hyperbilirubinemia in Term Appropriate-for-Gestational-Age (AGA) Neonates
Cureus. 2026 Mar 15;18(3):e105278. doi: 10.7759/cureus.105278. eCollection 2026 Mar.ABSTRACTBACKGROUND: Jaundice is common in neonates, yet clinically significant hyperbilirubinemia may develop after early discharge. Bilirubin typically peaks between days 3 and 5; therefore, reliable predischarge biomarkers could improve risk stratification and follow-up planning. This study assessed whether cord blood total serum bilirubin (TSB) and 24…
The enhancing therapeutic effect of neonatal jaundice by bifidobacterium through regulating inflammation and gut microbiota in combination with phototherapy-a randomized controlled trial
Front Microbiol. 2026 Apr 1;17:1761245. doi: 10.3389/fmicb.2026.1761245. eCollection 2026.ABSTRACTBACKGROUND: Hyperbilirubinemia is among the most common conditions in neonates, and phototherapy is currently the most widely used treatment. However, it can induce side effects such as skin rashes, diarrhea, and gut microbiota dysbiosis, particularly affecting Bifidobacterium levels. This study aimed to investigate whether …
Effect of skin color and other skin properties on the delivered light dose in phototherapy for neonatal hyperbilirubinemia
Biophotonics Discov. 2025 Aug 8;2(3):032508. doi: 10.1117/1.BIOS.2.3.032508. eCollection 2025 Jul.ABSTRACTSIGNIFICANCE: Hyperbilirubinemia is a common and potentially harmful condition in newborn infants. Phototherapy is the primary treatment for critically high bilirubin levels. Yet, the impact of patient skin properties and the wavelength of the phototherapy light on the delivered light dose remains unclear.…
Effect of kangaroo mother care initiated within the first 24 h in preterm or low birth weight infants: A systematic review and meta-analysis
Int J Nurs Stud. 2026 Apr 20;179:105533. doi: 10.1016/j.ijnurstu.2026.105533. Online ahead of print.ABSTRACTBACKGROUND: In preterm or low birth weight newborns, kangaroo mother care offers relevant emotional, physiological and clinical benefits. However, uncertainty remains regarding the optimal timing for initiating this intervention.OBJECTIVE: This systematic review aims to evaluate the effects …
Kangaroo Care as an intervention in randomised controlled trials in neonatal intensive care
Pediatr Res. 2026 Apr 23. doi: 10.1038/s41390-026-05020-5. Online ahead of print.ABSTRACTKangaroo Care (KC) is an evidence-based intervention, with greatest benefit when initiated early and provided for continuous periods, as recommended by the World Health Organization. However, uncertainty remains around KC operationalisation in research settings and how this may …
Neurodevelopment after a strength-based intervention in children born extremely preterm: a randomised controlled trial
Pediatr Res. 2026 Apr 23. doi: 10.1038/s41390-026-04940-6. Online ahead of print.ABSTRACTBACKGROUND: Extremely preterm birth increases the risk of neurodevelopmental impairments. Early interventions supporting child and parent may improve child neurodevelopment, but evidence is limited. We aimed to evaluate the effect of the Stockholm Preterm Interaction-Based Intervention on neurodevelopmental …
Maternal Vitamin D Status, Oxidative Stress, and Implications for Neonatal Development: A Cross-Sectional Study
Metabolites. 2025 Dec 24;16(1):19. doi: 10.3390/metabo16010019.ABSTRACTBackground: Vitamin D (VD) plays a central role in calcium homeostasis during pregnancy and has been implicated in redox-related biological processes. While VD deficiency (VDD) has been consistently associated with adverse pregnancy outcomes, the relationships between VD insufficiency (VDI), maternal antioxidant-related biomarkers, and neonatal outcomes remain …
Pediatr Res. 2026 Feb 2. doi: 10.1038/s41390-026-04780-4. Online ahead of print.ABSTRACTThe trajectory of sleep in the first year of age is highly dynamic and correlates with developmental progress from the neonatal to the infantile period. During this critical period of brain growth, sleep facilitates neural maturation and memory …
Role of Glutamate Receptor-Related Genes in Myopia Occurrence and Visual Development
Curr Eye Res. 2026 Mar 10:1-11. doi: 10.1080/02713683.2026.2637650. Online ahead of print.ABSTRACTPURPOSE: Abnormal expression of glutamate receptors is believed to be associated with myopia. However, it is currently unclear which genes contribute to the occurrence of such diseases. This study aims to investigate the effects of glutamate receptor-related genes family on …
Challenges and limitations of evaluating the efficacy of music intervention for preterm infants: auditory development, methodological heterogeneity, medical complexity, parental involvement and environmental barriers
Front Pediatr. 2026 Feb 26;14:1716416. doi: 10.3389/fped.2026.1716416. eCollection 2026.ABSTRACTDespite growing interest in music therapy (MT) as a supportive intervention in neonatal intensive care units (NICUs), strong evidence for its long-term efficacy remains scarce. This perspective article explores the multifaceted challenges of implementing and evaluating MT in NICUs, particularly for preterm infants. These …
Implementation of developmental care in routine NICU practice and early clinical outcomes in preterm infants
Front Pediatr. 2026 Mar 18;14:1794146. doi: 10.3389/fped.2026.1794146. eCollection 2026.ABSTRACTINTRODUCTION: Despite improved survival of preterm infants, neonatal complications and long-term morbidity remain high, highlighting the need for optimized care in neonatal intensive care units. Developmental care aims to reduce stress and better align the extrauterine environment with intrauterine conditions, and has been associated …
Developmental follow-up, surveillance and support at the age of 4 years: a best practice guide from the British Association for Neonatal Neurodevelopmental Follow-Up
Arch Dis Child Fetal Neonatal Ed. 2026 Apr 29:fetalneonatal-2026-330533. doi: 10.1136/archdischild-2026-330533. Online ahead of print.ABSTRACTDevelopmental follow-up is a necessary part of neonatal care to identify additional support needs but also to allow national surveillance and research. Follow-up at 4 years of age enables assessment before school entry, allowing schools …
Hémorragie intra-ventriculaire et dilatation ventriculaire post-hémorragique
Does Necrotizing Enterocolitis Severity and Timing, Rather than Necrotizing Enterocolitis Itself, Drive Shunt Failure in Premature Infants with Posthemorrhagic Hydrocephalus?
J Pediatr. 2026 Feb 26;293:115048. doi: 10.1016/j.jpeds.2026.115048. Online ahead of print.NO ABSTRACTPMID:41763598 | DOI:10.1016/j.jpeds.2026.115048
Neurodevelopmental impairment in preterm infants following progressive post-hemorrhagic ventricular dilatation
J Perinatol. 2026 Mar 13. doi: 10.1038/s41372-026-02614-z. Online ahead of print.ABSTRACTOBJECTIVE: To investigate the relationship of post-hemorrhagic ventricular dilatation (PHVD) with neurodevelopmental outcomes in preterm infants.STUDY DESIGN: Retrospective cohort study of infants
Impact of ultrasound-guided circulatory management protocol on intraventricular hemorrhage in extremely preterm infants
Pediatr Res. 2026 Feb 28. doi: 10.1038/s41390-026-04863-2. Online ahead of print.ABSTRACTBACKGROUND: Intraventricular hemorrhage (IVH) is a serious complication in extremely preterm infants, in whom the first 72 hours of life are critical. We evaluated the impact of an ultrasound-guided circulatory management protocol on IVH incidence.METHODS: This retrospective study …
Wide variation in death rates and post-hemorrhagic hydrocephalus (PHH) treatment in preterm severe intraventricular hemorrhage (IVH)
J Perinatol. 2026 Feb 16. doi: 10.1038/s41372-025-02528-2. Online ahead of print.ABSTRACTOBJECTIVE: Determine if decreased rates of severe IVH in VLBW infants in California translated to decreased rates of infant death or PHH treatment among those with severe IVH, and to evaluate variations in neurosurgical treatment of neonatal PHH.…
Risk factors for early mortality and severe intraventricular hemorrhage in extremely preterm infants with gestational age
Front Pediatr. 2026 Jan 15;13:1715767. doi: 10.3389/fped.2025.1715767. eCollection 2025.ABSTRACTINTRODUCTION: Extremely premature infants (EPIs) are at significant risk for early mortality and severe intraventricular hemorrhage. This study aimed to investigate the risk factors associated with early mortality and severe intraventricular hemorrhage in EPIs with a gestational age of less than 28 weeks and to …
Intraventricular hemorrhage profile in very low birth weight preterm infants (< 1000 g and 1000 g) at a tertiary center in Sao Paulo State over a decade
Clinics (Sao Paulo). 2026 Mar 23;81:100914. doi: 10.1016/j.clinsp.2026.100914. Online ahead of print.ABSTRACTOBJECTIVE: The better survival of preterm infants in recent years raises concerns about the risk of Intraventricular Hemorrhage (IVH). The authors investigated the incidence, risk factors, severity, and mortality of IVH in Very Low Birth Weight (VLBW) infants, comparing …
The association between mode of delivery and severe intraventricular hemorrhage in very preterm infants
J Matern Fetal Neonatal Med. 2026 Dec;39(1):2650951. doi: 10.1080/14767058.2026.2650951. Epub 2026 Mar 29.ABSTRACTBACKGROUND: Infants born before 32 weeks of gestation are at high risk of developing intraventricular hemorrhage (IVH), which is associated with significant mortality and morbidity as well as long-term neurodevelopmental impairment. There is currently a lack of consensus regarding the impact of …
Association of Day-1 Hemoglobin Oxygen Affinity (p50) with Severe Intraventricular Hemorrhage in Preterm Infants
Indian Pediatr. 2026 Apr 8. doi: 10.1007/s13312-026-00329-0. Online ahead of print.ABSTRACTOBJECTIVE: The partial pressure of oxygen at which hemoglobin is saturated at 50% (p50) reflects the balance between oxygen loading and tissue unloading. This study was conducted to ascertain if a lower p50 is linked to a greater incidence …
Predictive model for severe intraventricular hemorrhage risk in preterm infants: a systematic review and meta-analysis
Front Pediatr. 2026 Apr 7;14:1785442. doi: 10.3389/fped.2026.1785442. eCollection 2026.ABSTRACTOBJECTIVE: Risk prediction models offer a potential approach for early identification of severe intraventricular hemorrhage (SIVH) in preterm infants, yet their clinical applicability and methodological quality remain uncertain. This systematic review aimed to identify existing SIVH prediction models in preterm infants, evaluate their performance, …
Early management of preterm infants in neonatal intensive care units (excluding respiratory diseases and ulcerative necrotizing enterocolitis)
Rev Prat. 2026 Mar;76(3):269-275.ABSTRACTPreterm neonates present multiple challenges due to organ immaturity.Cardiovascular:Patent ductus arteriosus (PDA) is common in lower gestational ages and may cause respiratory and circulatory complications. Treatment includes medical (ibuprofen, para-cetamol), surgical, or percutaneous approaches. Bradycardia is frequent and requires continuous monitoring.Digestive/Metabolic:Early …
Transfer learning prediction of surgical necrotizing enterocolitis in preterm infants without pneumoperitoneum on abdominal X-ray
Transl Pediatr. 2026 Mar 23;15(3):68. doi: 10.21037/tp-2025-1-867. Epub 2026 Feb 27.ABSTRACTBACKGROUND: Necrotizing enterocolitis (NEC) remains a leading cause of mortality in preterm infants, with 30-39% requiring surgical intervention. However, existing models for predicting surgical NEC lack accuracy and clinical utility, especially for infants without pneumoperitoneum on abdominal X-ray (AXR). In this …
Early enteral nutrition practices and their association with growth and necrotising enterocolitis in extremely preterm infants-A dual national cohort study
Pediatr Res. 2026 Apr 7. doi: 10.1038/s41390-026-04849-0. Online ahead of print.ABSTRACTBACKGROUND: In Sweden, the incidence of necrotising enterocolitis (NEC) in extremely preterm infants has increased from 6 to 10% over a decade. We examined whether changes in enteral nutrition during the first 2 weeks were associated with growth and development of …
Role of melatonin for prevention of necrotizing enterocolitis in preterm infants: a randomized controlled trial
J Trop Pediatr. 2026 Feb 9;72(2):fmag020. doi: 10.1093/tropej/fmag020.ABSTRACTFeeding intolerance (FI) in preterm infants may signal necrotizing enterocolitis (NEC), in which oxidative stress (OS) plays a central role. Melatonin has demonstrated promise in mitigating neonatal OS-related diseases. The study is aimed to assess the effect of enteral melatonin on the …
A Review of Probiotic Interventions for Necrotizing Enterocolitis and Sepsis in Preterm Infants
Int J Mol Sci. 2026 Apr 17;27(8):3602. doi: 10.3390/ijms27083602.ABSTRACTNecrotizing enterocolitis (NEC) and sepsis/late-onset sepsis (LOS) are significant contributors to preterm infant morbidity and mortality, with prematurity and low birth weight representing major risk factors for these interconnected conditions. Although the pathogenesis of NEC and LOS is not fully understood, there …
Does Necrotizing Enterocolitis Severity and Timing, Rather than Necrotizing Enterocolitis Itself, Drive Shunt Failure in Premature Infants with Posthemorrhagic Hydrocephalus?
J Pediatr. 2026 Feb 26;293:115048. doi: 10.1016/j.jpeds.2026.115048. Online ahead of print.NO ABSTRACTPMID:41763598 | DOI:10.1016/j.jpeds.2026.115048
Neurodevelopmental impairment in preterm infants following progressive post-hemorrhagic ventricular dilatation
J Perinatol. 2026 Mar 13. doi: 10.1038/s41372-026-02614-z. Online ahead of print.ABSTRACTOBJECTIVE: To investigate the relationship of post-hemorrhagic ventricular dilatation (PHVD) with neurodevelopmental outcomes in preterm infants.STUDY DESIGN: Retrospective cohort study of infants
Impact of ultrasound-guided circulatory management protocol on intraventricular hemorrhage in extremely preterm infants
Pediatr Res. 2026 Feb 28. doi: 10.1038/s41390-026-04863-2. Online ahead of print.ABSTRACTBACKGROUND: Intraventricular hemorrhage (IVH) is a serious complication in extremely preterm infants, in whom the first 72 hours of life are critical. We evaluated the impact of an ultrasound-guided circulatory management protocol on IVH incidence.METHODS: This retrospective study …
Wide variation in death rates and post-hemorrhagic hydrocephalus (PHH) treatment in preterm severe intraventricular hemorrhage (IVH)
J Perinatol. 2026 Feb 16. doi: 10.1038/s41372-025-02528-2. Online ahead of print.ABSTRACTOBJECTIVE: Determine if decreased rates of severe IVH in VLBW infants in California translated to decreased rates of infant death or PHH treatment among those with severe IVH, and to evaluate variations in neurosurgical treatment of neonatal PHH.…
Risk factors for early mortality and severe intraventricular hemorrhage in extremely preterm infants with gestational age
Front Pediatr. 2026 Jan 15;13:1715767. doi: 10.3389/fped.2025.1715767. eCollection 2025.ABSTRACTINTRODUCTION: Extremely premature infants (EPIs) are at significant risk for early mortality and severe intraventricular hemorrhage. This study aimed to investigate the risk factors associated with early mortality and severe intraventricular hemorrhage in EPIs with a gestational age of less than 28 weeks and to …
Summary of best evidence on parental involvement in neonatal intensive care units: integrating family-centered and family-integrated care models
Glob Health Action. 2026 Dec;19(1):2653286. doi: 10.1080/16549716.2026.2653286. Epub 2026 May 5.ABSTRACTFamily-Centered Care (FCC) and Family-Integrated Care (FICare) are widely adopted models in Neonatal Intensive Care Units (NICUs), designed to foster parental involvement and support both neonatal and family outcomes. This review synthesizes and critically appraises the best available evidence on FCC and FICare …
Parental involvement in neonatal decision-making: a narrative review
Front Pediatr. 2026 Apr 20;14:1803025. doi: 10.3389/fped.2026.1803025. eCollection 2026.ABSTRACTIn the neonatal intensive care unit (NICU), parents are frequently required to make preference-sensitive decisions under prognostic uncertainty and severe time pressure. Although family-centered care and shared decision-making (SDM) are widely advocated, evidence on how parental involvement varies across neonatal decision contexts remains fragmented. …
Ethical and management dilemmas in the care of the newborn at the limit of viability: a narrative review
J Med Life. 2026 Feb;19(2):89-97. doi: 10.25122/jml-2026-0020.ABSTRACTThere are variations among healthcare providers regarding the gestational age considered the threshold of viability. Currently, the World Health Organization sets the lower limit of viability at 22 weeks of gestation, or a birth weight of 500 g, or a birth length of 25 cm. …
Relationship between thyroid hormones and bronchopulmonary dysplasia in extremely and very preterm infants
Front Physiol. 2026 Apr 13;17:1818723. doi: 10.3389/fphys.2026.1818723. eCollection 2026.ABSTRACTAIMS: Thyroid hormones (THs) play a vital role in neonatal development. The present study aimed to evaluate the association between thyroid function and bronchopulmonary dysplasia (BPD) incidence as well as neurodevelopment in extremely and very preterm infants.METHODS: This retrospective study involved 125 preterm infants …
Noninvasive Neurally Adjusted Ventilatory Assist for the Management of Severe Tracheobronchomalacia in a Preterm Infant With Bronchopulmonary Dysplasia: A Case Report
The impact of bronchopulmonary dysplasia on post-neonatal intensive care treatment for retinopathy of prematurity in very preterm infants
Early Hum Dev. 2026 Apr 17;220:106570. doi: 10.1016/j.earlhumdev.2026.106570. Online ahead of print.ABSTRACTOBJECTIVE: To examine whether infants with bronchopulmonary dysplasia (BPD) are at higher risk for ROP treatment, and whether those with BPD discharged home on oxygen are at higher risk for ROP treatment after NICU discharge.METHODS: A cohort study …
