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Auteurs québécois: Joël Macoir, Monica Lavoie et Laura Monetta
ARTICLES
Aphasie primaire progressive
Applicability and Correlates of a Symptom-Led Staging System for Primary Progressive Aphasia
Eur J Neurol. 2025 Dec;32(12):e70472. doi: 10.1111/ene.70472.ABSTRACTBACKGROUND: This study aimed at assessing the applicability of a symptom-led staging system for primary progressive aphasia (PPA) based on retrospective medical records, as well as at exploring their demographic and clinical correlates.METHODS: 75 PPA patients (10 semantic, 28 non-fluent, 22 logopenic, and 16 mixed variants) were …
Baseline Functional Connectivity Predicts Who Will Benefit From Neuromodulation: Evidence From Primary Progressive Aphasia
Neurorehabil Neural Repair. 2026 Jan 9:15459683251395692. doi: 10.1177/15459683251395692. Online ahead of print.ABSTRACTBackgroundUnderstanding individual variability in response to interventions is essential for developing personalized treatment strategies. In rare and clinically heterogeneous conditions like primary progressive aphasia (PPA), predicting treatment response is particularly challenging due to varying clinical manifestations. In this study, we aimed …
Logopenic variant of primary progressive aphasia in a bilingual non-Alzheimer's disease octogenarian
Dement Neuropsychol. 2026 Jan 9;20:e20250379. doi: 10.1590/1980-5764-DN-2025-0379. eCollection 2026.ABSTRACTA highly educated and intellectually active 84-year-old male presented with word-finding pauses and impaired sentence repetition, with preserved single-word comprehension, reading, and writing, a clinical profile consistent with the logopenic variant of primary progressive aphasia (lvPPA). Interestingly, the initial symptom was …
Verbal learning in logopenic variant Primary Progressive Aphasia: An EEG investigation
Neurobiol Aging. 2025 Oct 10;157:60-67. doi: 10.1016/j.neurobiolaging.2025.10.002. Online ahead of print.ABSTRACTThe logopenic variant of PPA (lvPPA) is characterized by impaired single-word retrieval and impaired repetition, which suggests a phonological working memory impairment. Phonological working memory is an essential mechanism for verbal learning; thus, one would expect that the verbal …
Face and Content Validation of the 10-Item Communicative Participation Item Bank General Short Form for Primary Progressive Aphasia: A Cognitive Interviewing Study
Am J Speech Lang Pathol. 2025 Oct 17:1-18. doi: 10.1044/2025_AJSLP-25-00085. Online ahead of print.ABSTRACTPURPOSE: The purpose of this study was to evaluate the face and content validity of the 10-item Communicative Participation Item Bank (CPIB) General Short Form for persons with primary progressive aphasia (PPA) and their communication partners.…
Behavioral constructs and neural correlates of descriptive and responsive speech in post-stroke aphasia
Cortex. 2025 Dec 5;194:143-158. doi: 10.1016/j.cortex.2025.11.012. Online ahead of print.ABSTRACTDiscourse refers to language that extends beyond a single clause and is used to express ideas, feelings or to interact with others. Persons with post-stroke aphasia often encounter difficulties in discourse, which can severely impede everyday communication. In recent years, …
Playful speech in managing problematic responses in interaction involving Mandarin speakers with aphasia: A conversation analysis
Clin Linguist Phon. 2026 Jan 8:1-21. doi: 10.1080/02699206.2025.2555239. Online ahead of print.ABSTRACTPeople with aphasia (PWA) often experience difficulties in conversation. Conversational partners (CPs) regularly respond by initiating various forms of repair. Drawing on Conversation Analysis (CA), this study examines how CPs employ playful speech to manage problematic responses (e.g. delays, …
Comparing Word Elicitation Strategies for Individuals With Apraxia of Speech and Aphasia
Int J Lang Commun Disord. 2026 Jan-Feb;61(1):e70189. doi: 10.1111/1460-6984.70189.ABSTRACTINTRODUCTION: Following a stroke, some individuals experience aphasia, apraxia of speech (AOS), or both. When these disorders are severe, it can be challenging to determine whether the observed deficits stem from disruptions in linguistic-symbolic processes, as seen in aphasia, or from …
Using Open-Source Software to Help Spanish Speakers With Aphasia Learn Everyday Sentences: A Single-Case Experimental Design
Am J Speech Lang Pathol. 2026 Jan 13;35(1):83-97. doi: 10.1044/2025_AJSLP-24-00550. Epub 2025 Dec 22.ABSTRACTPURPOSE: There is a critical need to develop evidence-based and accessible interventions for Spanish speakers with aphasia (SSWA). Script training is a well-established treatment that helps people with aphasia learn sentences for daily-life situations, but its evidence comes …
Effects and Predictors of Two-Person Small Group Speech Therapy in Children With Language Disorder: A Retrospective Observational Study
Ann Rehabil Med. 2025 Dec;49(6):392-399. doi: 10.5535/arm.250123. Epub 2025 Dec 31.ABSTRACTOBJECTIVE: To investigate the effects of small group speech therapy consisting of two children in aspects of language and social development and identify powerful predictors for maximal therapeutic gains of two-person small-group speech therapy (2-SST).METHODS: We retrospectively reviewed the medical …
Maximising the Impact of Speech and Language Therapy for Children With Speech Sound Disorder (The MISLToe-SSD) Study: Developing a Core Outcome Set (COS) for Routine Data Collection From UK NHS Speech and Language Therapy Services
Int J Lang Commun Disord. 2026 Jan-Feb;61(1):e70188. doi: 10.1111/1460-6984.70188.ABSTRACTBACKGROUND: Children with speech sound disorder (SSD) are at risk of long-term adverse consequences if appropriate intervention is not provided in a timely way. Although there are interventions of proven efficacy, these are often not implemented with good fidelity in clinical …
Equitable speech technologies for older adults: a call to prioritize low resource languages
Gerontologist. 2025 Dec 29:gnaf315. doi: 10.1093/geront/gnaf315. Online ahead of print.ABSTRACTRecent advancements in artificial intelligence, particularly in speech technologies, hold significant potential for improving the health and wellbeing of older adults by offering non-invasive, accessible and scalable solutions to increase social engagement, assist with daily activities and diagnose disease. However, …
Prefrontal Speaker-Listener Neural Coupling Supports Speech-in-Noise Comprehension in Normal-Hearing Older Adults: An fNIRS Study
Eur J Neurosci. 2026 Jan;63(1):e70392. doi: 10.1111/ejn.70392.ABSTRACTDespite age-related declines in the structure and function of auditory and language-related regions, many older adults retain a relatively preserved ability to understand speech in noisy environments. However, the neural mechanisms supporting this ability remain unclear. In this study, 30 older adults (59-71 years) …
Dysarthria assessment in multiple sclerosis patients
Mult Scler. 2025 Dec 19:13524585251400108. doi: 10.1177/13524585251400108. Online ahead of print.ABSTRACTBACKGROUND: Speech patterns in multiple sclerosis (MS) are poorly characterized. Software such as Dysarthria Analyzer (DA) performs a detailed speech analysis.OBJECTIVE: The objective of the study is (1) to explore speech features in patients with MS and (2) to investigate correlations between speech …
Beyond manual transcripts: Exploring the potential of automatic speech recognition errors in improving Alzheimer's disease detection
J Biomed Inform. 2026 Jan;173:104968. doi: 10.1016/j.jbi.2025.104968. Epub 2025 Dec 18.ABSTRACTOBJECTIVE: This study aims to extend the counterintuitive observation that Automatic Speech Recognition (ASR) errors can be beneficial for Alzheimer's Disease (AD) detection. Our objective is to conduct a large-scale investigation to validate this phenomenon and, more importantly, to elucidate the …
Speech and language outcome measures in clinical trials of Alzheimer's and Parkinson's diseases
Expert Rev Neurother. 2026 Jan;26(1):15-34. doi: 10.1080/14737175.2025.2600616. Epub 2025 Dec 16.ABSTRACTINTRODUCTION: Alongside core diagnostic symptoms, Alzheimer's disease (AD) and Parkinson's disease (PD) involve early and pervasive speech-language impairments (SLI), often appearing in preclinical stages and capturing disease severity. However, speech language outcome measures are under-represented in clinical trials, missing out on critical …
Auteurs québécois: Joël Macoir, Monica Lavoie et Laura Monetta
Rethinking the diagnosis of primary progressive aphasia: current challenges and future directions
Front Aging Neurosci. 2025 Dec 3;17:1736855. doi: 10.3389/fnagi.2025.1736855. eCollection 2025.ABSTRACTPrimary progressive aphasia (PPA) is a clinical syndrome characterized by the progressive decline of language abilities due to neurodegenerative disease. Accurate and timely diagnosis is critical for effective clinical management, patient support, and research participation. However, several diagnostic challenges persist, including limitations in …
Effectiveness of a teletherapy-based phonological short-term memory training in reducing phonological impairments in the logopenic variant of primary progressive aphasia: a multiple case study
Front Hum Neurosci. 2025 Dec 18;19:1724345. doi: 10.3389/fnhum.2025.1724345. eCollection 2025.ABSTRACTThe logopenic variant of Primary Progressive Aphasia (lvPPA) is marked by phonological short-term memory deficits that compromise repetition and communication. While previous interventions in PPA have primarily targeted lexical-semantic abilities, little is known about therapies that directly address phonological impairments, primarily through teletherapy. …
