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Maladies chroniques et nutrition: Obésité, hypertension et diabète
Maladies gastro-intestinales
Dysphagie oropharyngée et dysphagie oesophagienne
Nutrition pédiatrique
Carences en vitamines et minéraux
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The role of nutrition-sensitive interventions in improving nutritional outcomes: findings from a systematic review and meta-analysis
Int J Equity Health. 2025 Nov 20;24(1):325. doi: 10.1186/s12939-025-02596-y.ABSTRACTBACKGROUND: Maternal and child undernutrition remains a major global health concern despite modest progress. Accelerating reductions in stunting and wasting will require increased investments in nutrition-sensitive interventions, which target nutrition impacts outside of the healthcare setting. This review examines the …
Newborn Screening Alone Cannot Prevent Most Cases of Severe Vitamin B12 Deficiency in the First Year of Life
Nutrients. 2025 Nov 16;17(22):3583. doi: 10.3390/nu17223583.ABSTRACTBACKGROUND/OBJECTIVES: Vitamin B12 (B12) is essential for the provision of methyl groups for numerous essential pathways. Infant B12 deficiency (B12D) can lead to severe, even irreversible neurological abnormalities. Maternal B12 status in pregnancy and during the breastfeeding period correlates significantly with the child's B12 …
Association between multimarkers of metabolic malnutrition and inflammation and risk of chronic obstructive pulmonary disease and lung function: a prospective cohort study of UK biobank
Nutr Metab (Lond). 2025 Nov 26;22(1):143. doi: 10.1186/s12986-025-01042-8.ABSTRACTBACKGROUND: Chronic obstructive pulmonary disease (COPD) pathogenesis involves the cross-links between inflammation, oxidative stress, and metabolic dysregulation leading to irreversible airflow limitation. The metabolic vulnerability index (MVX) integrates inflammation and metabolic malnutrition related metabolic biomarkers that may reflect these underlying mechanisms. …
Malnutrition After Malabsorptive Metabolic Bariatric Surgery: When Should the Surgery Be Reversed?
Cureus. 2025 Nov 26;17(11):e97830. doi: 10.7759/cureus.97830. eCollection 2025 Nov.ABSTRACTBACKGROUND: Metabolic bariatric surgery (MBS) is the most successful way to tackle obesity and its related diseases. However, long-term side effects can arise. One rare but serious complication is severe protein-energy malnutrition, which may need surgery to reverse the effects on gut absorption …
Is Vitamin D Fortification of Dairy Products Effective for Improving Vitamin D Status? A Systematic Review and Meta-Analysis of Randomised Controlled Trials
Nutrients. 2025 Nov 29;17(23):3757. doi: 10.3390/nu17233757.ABSTRACTBackground/objectives: Given the suboptimal vitamin D intake and status among the United Kingdom population, the Scientific Advisory Committee on Nutrition is seeking suitable food vehicles for vitamin D fortification. Thus, this study aimed to examine the efficacy of vitamin D-fortified dairy products in improving serum 25…
Enteral protein supplementation in critically ill trauma and surgical patients: A single-center randomized clinical trial
Author Names: O'Keefe G.E.,Brown S.P.,Shelton M.M.,Qiu Q.,Bisgaard E.K.,Wilson I.M.,Robinson J.L.,Roubik D.J.,Malloy A.,May S. Database Source: Embase Weekly Updates Journal Title: Journal of Trauma and Acute Care Surgery Article Title: Enteral protein supplementation in critically …
Front Nutr. 2025 Dec 8;12:1718116. doi: 10.3389/fnut.2025.1718116. eCollection 2025.ABSTRACTHome parenteral nutrition (HPN) is the primary life-saving therapy for patients with chronic intestinal failure (CIF). Patients requiring palliative nutrition, such as those with advanced cancer, may also benefit from HPN. Lipids are an integral part of parenteral nutrition (PN), but the use of …
Evaluation of Serum Zinc Status in Patients With Neurologic Impairment Under Controlled Enteral Nutrition
Cureus. 2025 Dec 1;17(12):e98266. doi: 10.7759/cureus.98266. eCollection 2025 Dec.ABSTRACTBACKGROUND: Patients with neurologic impairment (NI) often require long-term enteral nutrition. Zinc plays a vital role in neurological and immune function, yet data on zinc intake and status in NI patients remain limited. This study aimed to evaluate whether serum zinc concentrations reflect …
Parenteral nutrition after major elective upper gastrointestinal surgery: A descriptive cohort study
JPEN J Parenter Enteral Nutr. 2026 Jan 6. doi: 10.1002/jpen.70040. Online ahead of print.ABSTRACTBACKGROUND: Patients undergoing major upper gastrointestinal surgery are at high nutrition risk, with central or peripheral parenteral nutrition an option when oral or enteral nutrition are not possible. We aimed to determine the number of patients who were …
Impact of Personalized Parenteral Nutrition on Inflammatory Markers and Clinical Outcomes in Critically Ill Patients: A Systematic Review and Meta-analysis
Indian J Crit Care Med. 2025 Dec;29(12):1040-1049. doi: 10.5005/jp-journals-10071-25089. Epub 2025 Dec 19.ABSTRACTBACKGROUND AND AIMS: Personalized parenteral nutrition (PPN) is a customized strategy to address the individual metabolic and nutritional requirements of the critically ill patients, especially in cases where enteral nutrition (EN) is not possible. However, available evidence regarding …
Enteral Nutrition Leads to Less-Severe Gastrointestinal Mucositis and Fewer Days of Nutritional Support as Compared to Parenteral Nutrition Among Autologous Transplant Patients in a Randomized Study
Author Names: Resvick H.,Hartman B.,Sigfrid C.,Friscioni V.,Madill J.,Cruikshank E.,Abouzeenni M.,Fulford A.,Xenocostas A.,Arntfield R.,Deotare U. Database Source: Embase Daily Updates Journal Title: Current Oncology Article Title: Enteral Nutrition Leads to Less-Severe Gastrointestinal Mucositis and Fewer Days of Nutritional Support as Compared …
Effect of combined ustekinumab and partial enteral nutrition on clinical and nutritional outcomes in Crohn's disease
Medicine (Baltimore). 2026 Jan 9;105(2):e46698. doi: 10.1097/MD.0000000000046698.ABSTRACTUstekinumab (UST), as a novel biologic agent, is approved globally for the treatment of Crohn's disease (CD). However, a subset of patients exhibit either no response or only a weak response to UST. Compared with normal diet, Partial Enteral Nutrition (PEN) appears to be …
Metabolic profiles in adults with trauma receiving enteral nutrition support: A metabolomic cohort study
JPEN J Parenter Enteral Nutr. 2026 Jan 11. doi: 10.1002/jpen.70051. Online ahead of print.ABSTRACTBACKGROUND: We aimed to identify metabolic changes after injury and potential mechanisms whereby nutrition support may influence metabolites and pathways. We analyzed 45 metabolites in 67 trauma patients.METHODS: We performed a metabolomic cohort study in critically ill adults with …
Implementation of an Enteral Nutrition Protocol in the Cardiac Care Unit - A Retrospective Study of Critically Ill Cardiovascular Patients
Circ Rep. 2025 Nov 5;8(1):127-135. doi: 10.1253/circrep.CR-25-0113. eCollection 2026 Jan 9.ABSTRACTBACKGROUND: Enteral nutrition (EN) is often delayed in critically ill cardiovascular patients due to concerns about bowel ischemia, especially when under vasopressor or mechanical support. We evaluated the impact of a structured EN protocol designed to promote timely and safe …
Maladies chroniques et nutrition: Obésité, hypertension et diabète
Maternal Nutrition, Toxicants, and Epigenetic Programming of Obesity Across Generations
Diabetes Metab Syndr Obes. 2025 Dec 31;18:4873-4911. doi: 10.2147/DMSO.S579409. eCollection 2025.ABSTRACTBACKGROUND: The developmental origins of health and disease (DOHaD) framework highlights the importance of the intrauterine environment in shaping lifelong health outcomes. Maternal nutrition, toxic exposures, and epigenetic reprogramming are key factors influencing offspring susceptibility to obesity and cardiometabolic disorders. …
Precision nutrition for hypertension: tea, coffee, antioxidant vitamins interactions with polygenic risk in multi-ethnic populations
Eur J Clin Nutr. 2026 Jan 8. doi: 10.1038/s41430-025-01699-7. Online ahead of print.ABSTRACTBACKGROUND AND OBJECTIVE: Hypertension is influenced by both genetic and dietary factors. Understanding gene-diet interactions across populations is key to precision prevention.OBJECTIVES: To identify genetic variants associated with hypertension in KoGES and UK Biobank (UKBB), …
Reshaping the Gut: Symptoms, Nutrition and Microbiota After Bariatric and Endoscopic Procedures in Obesity
Nutrients. 2025 Dec 28;18(1):108. doi: 10.3390/nu18010108.ABSTRACTObesity is a multifactorial disease linked to chronic inflammation, metabolic disorders, and gut microbiota dysbiosis. Bariatric surgery (BS) and endoscopic sleeve gastroplasty (ESG) are effective for sustained weight loss and comorbidity improvement but may cause gastrointestinal and nutritional complications. This narrative review, informed by a structured …
Systematic review of clinical practice guidelines to identify nutritional recommendations for the ambulatory management of type 2 diabetes mellitus
Nutr Hosp. 2025 Dec 3. doi: 10.20960/nh.05760. Online ahead of print.ABSTRACTOBJECTIVE: to identify and analyze the nutritional recommendations of clinical practice guidelines (GPC) for the ambulatory management of adult patients with type 2 diabetes mellitus (DM2).METHODOLOGY: a systematic review of the literature focused on the identification of recommendations for the ambulatory …
AOM (Anti-Obesity Medication) weight loss: do we see the same nutritional issues as metabolic surgery?
Author Names: Smith C.,South T.-L.,Willis L. Database Source: Embase Daily Updates Journal Title: Obesity Surgery Article Title: AOM (Anti-Obesity Medication) weight loss: do we see the same nutritional issues as metabolic surgery? Year: 2024 Issue: Supplement 2 Volume: 34 Abstract: Background: Clinical practice with bariatric health has known management requirements …
Effects of a 12-week combined exercise-nutrition intervention on body composition, physical fitness, and lifestyle disease indicators in women with normal weight obesity
Phys Act Nutr. 2025 Dec;29(4):57-63. doi: 10.20463/pan.2025.0035. Epub 2025 Dec 30.ABSTRACTPURPOSE: This study investigated the effects of 12 weeks of nutrition education and combined exercise training on body composition, physical fitness, and lifestyle disease indicators in women with normal weight obesity (NWO).METHODS: Twenty-six women with NWO in their 30s (BMI 18.5-22.9 …
Pulmonary hypertension and nutrition: Survey of uk patients
Author Names: Armstrong I.,Clayton S.,Billings C.,Sephton P.,Ferguson M.,Smith J. Database Source: Embase Daily Updates Journal Title: John Wiley and Sons Inc Article Title: Pulmonary hypertension and nutrition: Survey of uk patients Year: 2024 Issue: 2 Volume: 14 Abstract: Nutritional deficiencies have been described in patients with pulmonary arterial …
Nutritional Intervention and Physical Activity in Adolescents and Children with Obesity
Nutrients. 2025 Dec 28;18(1):101. doi: 10.3390/nu18010101.ABSTRACTThe scientific evidence on nutrition, lifestyle behaviours, and child and adolescent health highlights a reality increasingly shared at the global level: dietary patterns, physical activity levels, sleep habits, and the use of digital technologies are undergoing rapid and interconnected changes that carry significant implications for the …
Nutritional Interventions for Childhood Obesity - a cross-sectional study
Author Names: Pradeep D. Database Source: Embase Daily Updates Journal Title: Journal of Cardiovascular Disease Research Article Title: Nutritional Interventions for Childhood Obesity - a cross-sectional study Year: 2021 Issue: 9 Volume: 12 Abstract: Introduction: Childhood obesity has become a global public health concern, predisposing affected individuals to various health complications. Despite efforts …
Nutritional management in functional dyspepsia and gastroparesis
Best Pract Res Clin Gastroenterol. 2025 Dec;79:102079. doi: 10.1016/j.bpg.2025.102079. Epub 2025 Dec 9.ABSTRACTFunctional dyspepsia (FD) and gastroparesis (GP) are chronic upper gastrointestinal disorders in which symptoms are closely linked to food intake. However, dietary interventions remain insufficiently studied, and the clinical overlap between the two conditions poses challenges for study design …
Oral nutritional management in short bowel syndrome
Best Pract Res Clin Gastroenterol. 2025 Dec;79:102082. doi: 10.1016/j.bpg.2025.102082. Epub 2025 Dec 9.ABSTRACTPatients with short bowel syndrome (SBS) have less than 200 cm of functional small intestine resulting in significantly impaired digestion and absorption of nutrients and fluids. When malabsorption becomes severe and cannot be compensated by oral intake, patients develop intestinal …
Impact of Ultrasound-Treated Emulsion Gels on the Structure of Purees for Oropharyngeal Dysphagia
Molecules. 2025 Oct 1;30(19):3933. doi: 10.3390/molecules30193933.ABSTRACTThis study investigated the effects of inulin concentration and ultrasonic homogenization on the particle size distribution and microstructure of oil-in-water emulsion gels stabilized with psyllium husk. These gels were then incorporated into meal purees formulated for individuals with dysphagia. Under ultrasound treatment, an increase in inulin …
Oropharyngeal Dysphagia and Odynophagia in Patients with Thermal Burn Injuries
Dysphagia. 2025 Oct 14. doi: 10.1007/s00455-025-10878-4. Online ahead of print.ABSTRACTDysphagia and odynophagia pose significant challenges to the overall well-being and recovery of patients after thermal burn injuries. This study aims to document the clinical presentation of oropharyngeal dysphagia and odynophagia in dysphagic patients with thermal burn injuries. Twenty-five …
Training as a strategy to improve care for patients with oropharyngeal dysphagia
Rehabilitacion (Madr). 2025 Oct-Dec;59(4):100948. doi: 10.1016/j.rh.2025.100948. Epub 2025 Oct 29.ABSTRACTINTRODUCTION: Oropharyngeal dysphagia (OD) is a common syndrome with significant clinical consequences, whose early detection and management require specific knowledge. Raising awareness and providing continuing education for healthcare professionals are essential to improve its management.OBJECTIVE: To assess participation rates and perceived …
Purinergic Signaling in Swallowing Reflex Initiation: Mechanisms and Therapeutic Implications for Oropharyngeal Dysphagia-A Narrative Review
Cells. 2025 Nov 14;14(22):1795. doi: 10.3390/cells14221795.ABSTRACTThe swallowing reflex is a highly coordinated process that is essential for safe bolus transit and airway protection. Although its neurophysiological framework has been extensively studied, the molecular mechanisms underlying reflex initiation remain incompletely understood, limiting targeted therapies for oropharyngeal dysphagia. Recent evidence implicates purinergic signaling …
Oropharyngeal dysphagia: a narrative review towards an integrated neurogeriatric perspective
Lancet Healthy Longev. 2025 Dec;6(12):100794. doi: 10.1016/j.lanhl.2025.100794. Epub 2025 Dec 2.ABSTRACTOropharyngeal dysphagia, prevalent in neurogeriatric populations, increases the risks of malnutrition, pneumonia, and mortality. Oropharyngeal dysphagia manifests as a multi-aetiological syndrome with diverse phenotypes. We advocate for a neurogeriatric perspective that integrates specific neurological insights with geriatric care principles to improve …
Dental Factors Associated With Oropharyngeal Dysphagia in Institutionalised Older Adults: A Systematic Review
Gerodontology. 2025 Dec 18. doi: 10.1111/ger.70034. Online ahead of print.ABSTRACTBACKGROUND: Aging is associated with a decline in physiological functions. Dysphagia, a disorder among older adults, impairs feeding and is related to morphological and functional changes in the stomatognathic system, which worsen with age-related physiological decline, particularly among institutionalised older adults.OBJECTIVE: …
The Impact of the Mediterranean Diet, Physical Activity, and Nutrition Education on Pediatric Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Review
Nutrients. 2025 Dec 20;18(1):28. doi: 10.3390/nu18010028.ABSTRACTBackground/Objectives: Metabolic dysfunction-associated steatotic liver disease (MASLD) is now the most prevalent chronic liver disorder among children and adolescents, mirroring the rise in pediatric obesity. The Mediterranean diet (MD) has demonstrated anti-inflammatory, antioxidant, and beneficial effects on different health outcomes across different life stages. The …
Nutrition and healthy lifestyles for children and adolescents with early-stage type 1 diabetes
Horm Res Paediatr. 2026 Jan 12:1-20. doi: 10.1159/000550434. Online ahead of print.ABSTRACTIncreasingly children and adolescents are being identified in early-stage type 1 diabetes (T1D), defined as two or more islet autoantibodies without hyperglycemia (above diagnostic threshold) or reliance on intensive insulin therapy. They require clinical monitoring and care. Healthy lifestyle education …
Combining thiopurine with partial enteral nutrition promotes complete mucosal healing in pediatric Crohn's disease
Pediatr Int. 2026 Jan-Dec;68(1):e70290. doi: 10.1111/ped.70290.ABSTRACTBACKGROUND: The combination of thiopurines and partial enteral nutrition (TP/PEN) is a common maintenance therapy for mild-to-moderate Crohn's disease (CD) in pediatric patients. However, no studies have investigated the efficacy of TP/PEN. This study aimed to evaluate the non-relapse and complete mucosal …
Association of Vitamin D Deficiency with Diabetic Nephropathy in Type 2 Diabetes: A Hospital-Based Cross-Sectional Study
Diseases. 2025 Dec 17;13(12):405. doi: 10.3390/diseases13120405.ABSTRACTBACKGROUND/OBJECTIVE: Diabetic nephropathy (DN), a key microvascular complication of type 2 diabetes (T2DM), drives significant morbidity, mortality, and healthcare costs. Vitamin D deficiency has been linked to renal dysfunction, but its role in DN remains unclear. This study assessed the association between vitamin D status …
Doctor-diagnosed sleep disorders in the United States: Prevalence and impact of tobacco smoke exposure and vitamin D deficiency. A population-based study
Front Sleep. 2023 Apr 3;2:1113946. doi: 10.3389/frsle.2023.1113946. eCollection 2023.ABSTRACTBACKGROUND AND PURPOSE: We determined the prevalence of physician-diagnosed sleep disorder and its association with tobacco smoke exposure and vitamin D deficiency.METHODS: The National Health and Nutrition Examination Survey (NHANES) of 2011-2012 data base was used for the study. Subjects were asked two …
The top 50 cited publications in the field of vitamin B12 deficiency: A bibliometric analysis review
J Family Med Prim Care. 2025 Nov;14(11):4457-4465. doi: 10.4103/jfmpc.jfmpc_2096_24. Epub 2025 Nov 29.ABSTRACTBACKGROUND: Vitamin B12 deficiency is a significant nutritional concern linked to megaloblastic anemia and neurological complications, and high-quality research is essential to address these health issues effectively. While highly cited publications have substantial influence on the field, there …
Metformin Induced Vitamin B12 deficiency: A Cross sectional study. Untangling the connection
Clin Med Insights Endocrinol Diabetes. 2025 Dec 18;18:11795514251357419. doi: 10.1177/11795514251357419. eCollection 2025.ABSTRACTBACKGROUND: Metformin is a widely popular drug to treat type 2 diabetes as it is efficacious, inexpensive and relatively well tolerated with minimal side effect profile. It is known that long term metformin use predisposes a person to develop Vitamin B12 deficiency, however …
Manganese Deficiency and Mn(2)O(3) Nanoparticles Supplementation Disrupt Bone Remodeling and Mineral Matrix Maturation in Rats
Int J Mol Sci. 2025 Dec 23;27(1):153. doi: 10.3390/ijms27010153.ABSTRACTThis study aimed to investigate the effects of dietary manganese deficiency and compare the impact of manganese macroparticles (MnCO3) and nanoparticles (Mn2O3NPs) on bone remodeling and metabolism. Twenty-seven male Wistar rats were divided into three groups (n = 9): control (standard MnCO3, 65 mg …
Vitamin B12 deficiency in metformin-treated community-dwelling older adults with diabetes: A cross-sectional multicentre study in Perak
Malays Fam Physician. 2025 Dec 22;20:79-100. doi: 10.51866/oa.718. eCollection 2025.ABSTRACTINTRODUCTION: Surveillance studies have shown a high prevalence of vitamin B12 deficiency in metformin-treated adults. Community-dwelling older adults have a higher risk of vitamin B12 deficiency due to lower gut absorption. To date, data on this specific cohort are lacking. We aimed …