Auteurs québécois: Joël Macoir, Monica Lavoie et Laura Monetta
ARTICLES
Aphasie primaire progressive
Investigating changes in connected speech in nonfluent/agrammatic primary progressive aphasia following script training
Cortex. 2025 Feb;183:193-210. doi: 10.1016/j.cortex.2024.09.019. Epub 2024 Dec 4.ABSTRACTScript training is a speech-language intervention designed to promote fluent connected speech via repeated rehearsal of functional content. This type of treatment has proven beneficial for individuals with aphasia and apraxia of speech caused by stroke and, more recently, for individuals with …
aFTLD-U presenting with primary progressive aphasia suggestive of non-fluent type with apraxia of speech
Neurocase. 2025 Feb 11:1-4. doi: 10.1080/13554794.2025.2464549. Online ahead of print.ABSTRACTAtypical frontotemporal lobar degeneration with ubiquitin-positive inclusions (aFTLD-U) is a rare subtype of Frontotemporal Lobar Degeneration. aFTLD-U is reported with a typically young onset behavioral variant of frontotemporal dementia syndrome, more specifically with younger age, predominant hyperorality, obsessive-compulsive features, and severe caudate …
The Functional Origin of Oral Word Production Deficits in the Logopenic Variant of Primary Progressive Aphasia: A Systematic Review
Brain Sci. 2025 Jan 24;15(2):111. doi: 10.3390/brainsci15020111.ABSTRACTBACKGROUND/OBJECTIVES: Oral word production (OWP) deficits are prominent in the logopenic variant of primary progressive aphasia (lvPPA); however, their functional origin remains unclear. Some studies suggest a lexical, post-lexical, or even a combined functional origin of these deficits. The aim of the present study …
Cognitive profiles in primary progressive aphasia variants: A cross-cultural Australian and Spanish investigation
J Neurol Sci. 2025 Mar 6;472:123446. doi: 10.1016/j.jns.2025.123446. Online ahead of print.ABSTRACTBACKGROUND: The effect of cultural differences in neurodegenerative diseases is not well understood. We aimed to investigate the cognitive profiles of English- and Spanish-speaking individuals with primary progressive aphasia (PPA).METHODOLOGY: A comparative cross-sectional study was conducted with 461 participants: 215 …
Brain Perfusion, Atrophy, and Dopaminergic Changes in Amyloid Negative Logopenic Primary Progressive Aphasia
Sci Rep. 2025 Mar 11;15(1):8429. doi: 10.1038/s41598-025-90116-x.ABSTRACTAlthough most cases of logopenic variant primary progressive aphasia (lvPPA) are caused by Alzheimer's disease (AD), Lewy body disease (LBD) has also been reported. We assessed brain perfusion, atrophy, dopamine transporter (DAT) uptake, and language function among patients with lvPPA based on …
Swallowing disorders in cerebral palsy: a systematic review of oropharyngeal Dysphagia, nutritional impact, and health risks
Ital J Pediatr. 2025 Feb 22;51(1):57. doi: 10.1186/s13052-025-01903-1.ABSTRACTCerebral palsy (CP) is a permanent disorder affecting movement and posture due to nonprogressive brain issues, often leading to various sensory, cognitive, and musculoskeletal challenges. Among these complications, oropharyngeal dysphagia (OPD) is prevalent, impacting up to 85% of children with CP and …
Swallowing Evaluation in Post-COVID-19 Patients with Oropharyngeal Dysphagia
Dysphagia. 2025 Mar 5. doi: 10.1007/s00455-025-10810-w. Online ahead of print.ABSTRACTOropharyngeal dysphagia (OD) is a prevalent issue in hospitalized COVID-19 patients. This study aimed to determine swallowing abnormalities in post-COVID-19 patients with OD and to determine the potential risk factors of aspiration in patients who have recovered from COVID-19. …
Advancing Neuropsychological Rehabilitation in Primary Progressive Aphasia Based on Principles of Cognitive Neuroscience: A Scoping Review and Systematic Analysis of the Data
Brain Sci. 2024 Dec 8;14(12):1234. doi: 10.3390/brainsci14121234.ABSTRACTBackground/Objectives: This systematic review of neuropsychological rehabilitation strategies for primary progressive aphasia will consider recent developments in cognitive neuroscience, especially neuroimaging techniques such as EEG and fMRI, to outline how these tools might be integrated into clinical practice to maximize treatment outcomes. Methods: A …
Assessment of disease impact through health-related quality of life measurement in primary progressive aphasia
Alzheimers Dement (N Y). 2024 Nov 26;10(4):e12499. doi: 10.1002/trc2.12499. eCollection 2024 Oct-Dec.ABSTRACTINTRODUCTION: Measurements of health-related quality of life (HRQoL) are important for capturing disease impact beyond physical health and relative to other diseases but have rarely been assessed in primary progressive aphasia (PPA).METHODS: HRQoL was characterized overall, by sex and …
Comprehension of acoustically degraded emotional prosody in Alzheimer's disease and primary progressive aphasia
Sci Rep. 2024 Dec 28;14(1):31332. doi: 10.1038/s41598-024-82694-z.ABSTRACTPrevious research suggests that emotional prosody perception is impaired in neurodegenerative diseases like Alzheimer's disease (AD) and primary progressive aphasia (PPA). However, no previous research has investigated emotional prosody perception in these diseases under non-ideal listening conditions. We recruited 18 patients with AD, …
Investigating changes in connected speech in nonfluent/agrammatic primary progressive aphasia following script training
Cortex. 2024 Dec 4;183:193-210. doi: 10.1016/j.cortex.2024.09.019. Online ahead of print.ABSTRACTScript training is a speech-language intervention designed to promote fluent connected speech via repeated rehearsal of functional content. This type of treatment has proven beneficial for individuals with aphasia and apraxia of speech caused by stroke and, more recently, for …
Case Series of Right-Hemisphere Nonfluent Variant of Primary Progressive Aphasia
J Clin Neurol. 2025 Jan;21(1):3-12. doi: 10.3988/jcn.2023.0451.ABSTRACTBACKGROUND AND PURPOSE: Nonfluent variant primary progressive aphasia (nfvPPA) is a neurodegenerative disorder characterized by the progressive deterioration of language functions that typically appears with atrophy predominating in the left peri-insular region (left-nfvPPA) on imaging. While both left-dominant and right-dominant presentations have been …
An automated method for quantifying syntactic complexity of spontaneous speech in Primary Progressive Aphasia
Alzheimers Dement. 2025 Jan 9;20(Suppl 2):e087017. doi: 10.1002/alz.087017. eCollection 2024 Dec.ABSTRACTBACKGROUND: Reduced syntactic complexity is the predominant linguistic impairment unique to the nonfluent agrammatic variant of PPA (naPPA).Reliable, objective and automatic methods for assessing syntactic complexity are currently lacking. Here, we introduce an automatic method for quantifying syntactic complexity in …
Music To My Eyes? Exploring the pupil old/new effect to familiar and unfamiliar music in people with logopenic variant Primary Progressive Aphasia
Alzheimers Dement. 2025 Jan 9;20(Suppl 4):e084507. doi: 10.1002/alz.084507. eCollection 2024 Dec.ABSTRACTBACKGROUND: Responses to individualized music in people living with dementia can be indicated by both verbal and non‐verbal cues. Evidence suggests that elevated pupil dilation responses to familiar vs. unfamiliar music are preserved in people living with typical Alzheimer’s …
Effectiveness of French Phonological Components Analysis in individuals with chronic aphasia
Int J Lang Commun Disord. 2024 Nov-Dec;59(6):2239-2264. doi: 10.1111/1460-6984.13080. Epub 2024 Jun 21.ABSTRACTBACKGROUND: Over 50% of individuals with aphasia face ongoing word-finding issues. Studies have found phonologically oriented therapy helpful for English speakers, but this has not yet been studied in French. It is essential to assess the effectiveness of such a …
Resting-state connectivity enhancement in Aphasia patients post-speech therapy: a localization model
Brain Imaging Behav. 2025 Feb 3. doi: 10.1007/s11682-025-00968-0. Online ahead of print.ABSTRACTResting-state functional connectivity has become a valuable tool in studying post-stroke aphasia (PSA). However, the specific distribution of increased functional connectivity areas (IFCAs) in PSA patients after speech-language therapy (SLT) remains unclear, particularly compared with the intrinsic …
Speech Therapy Combined With Cerebrolysin in Enhancing Nonfluent Aphasia Recovery After Acute Ischemic Stroke: ESCAS Randomized Pilot Study
Stroke. 2025 Feb 17. doi: 10.1161/STROKEAHA.124.049834. Online ahead of print.ABSTRACTBACKGROUND: Stroke-induced aphasia significantly impacts communication and quality of life. Despite the standard treatment being speech and language therapy, outcomes vary, highlighting the need for additional therapies. Cerebrolysin, a neuroprotective and neurotrophic agent, has shown potential in stroke management. This study addresses …
Experiences and perspectives of UK speech and language therapists on telehealth assessment with people living with post-stroke aphasia
Int J Lang Commun Disord. 2025 Mar-Apr;60(2):e70018. doi: 10.1111/1460-6984.70018.ABSTRACTBACKGROUND: Stroke care in the UK was significantly affected by the COVID-19 pandemic, with many services switching to telehealth. Post-pandemic, a UK survey of speech and language therapists (SLTs) working with people with aphasia (PWA) showed the vast majority planned to …
Transcranial Magnetic Stimulation Combined With Multimodality Aphasia Therapy for Chronic Poststroke Aphasia: A Randomized Clinical Trial
Neurology. 2025 Mar 25;104(6):e213424. doi: 10.1212/WNL.0000000000213424. Epub 2025 Feb 25.ABSTRACTBACKGROUND AND OBJECTIVES: Intensive speech therapy may improve recovery from poststroke aphasia. Further evidence suggests that pairing repetitive transcranial magnetic stimulation (rTMS) with intensive speech therapy might augment outcomes. This sham-controlled randomized clinical trial evaluated the efficacy of 1-Hz rTMS over the right …
Leading the Way in Dementia Care: Embracing the Whole Person
Semin Speech Lang. 2024 Aug;45(4):368-380. doi: 10.1055/s-0044-1788799. Epub 2024 Jul 31.ABSTRACTAudrey Holland was a leading innovator and speech-language pathologist (SLP) in adult neurological communication disabilities for over five decades. She was a pioneer in the involvement of SLPs with people with dementia, inspiring both knowledge development and clinical practice regarding …
Enhancing Communication and Swallowing Skills in Children with Cri Du Chat Syndrome: A Comprehensive Speech Therapy Guide
Children (Basel). 2024 Dec 16;11(12):1526. doi: 10.3390/children11121526.ABSTRACTBackground: A specific deletion on the short arm of chromosome 5 (5p) is the hallmark of the rare genetic syndrome called Cri du Chat Syndrome (CdCS). It causes severe difficulty with swallowing, speech, motor skills, and cognitive deficiencies. These arise from characteristic laryngeal abnormalities and oral-motor …
The Active Ingredients of Semantic Naming Treatment: Evidence From Mandarin-English Bilingual Adults With Aphasia
J Speech Lang Hear Res. 2025 Jan 2;68(1):216-233. doi: 10.1044/2024_JSLHR-23-00705. Epub 2024 Dec 17.ABSTRACTPURPOSE: Following the Rehabilitation Treatment Specification System (RTSS) framework, the current study investigated the active ingredients in the modified semantic feature analysis (mSFA) targeting either noun or verb retrieval in Mandarin-English bilingual adults with aphasia (BWA).METHOD: Twelve …
Cognitive impairment in bilinguals with neurological diseases
Zh Nevrol Psikhiatr Im S S Korsakova. 2024;124(12):26-29. doi: 10.17116/jnevro202412412126.ABSTRACTBilingualism is widespread in the world and In Russia and in recent years has been actively considered within the framework of the cognitive reserve concept. The paper provides a review of articles studying cognitive functions in bilingual patients with neurological …
Advanced disconnectomic analyses reveal repetition pathways in a case of mixed transcortical aphasia
Brain Cogn. 2025 Feb;183:106257. doi: 10.1016/j.bandc.2024.106257. Epub 2024 Dec 27.ABSTRACTMixed Transcortical Aphasia (MTA) is an infrequent aphasic syndrome, characterized by poor comprehension and production in oral language abilities and poor performance in written language abilities. However, individuals with MTA typically retain the ability to repeat. Our patient, a woman who suffered …
The clinical practice of speech and language therapists with preschool-age children with syntactic impairment
Int J Lang Commun Disord. 2025 Mar-Apr;60(2):e70012. doi: 10.1111/1460-6984.70012.ABSTRACTBACKGROUND: Children with syntactic impairment associated with autism spectrum disorder and developmental language disorder benefit from speech and language therapy intervention. Despite that, few studies focus on the clinical practice of the speech and language therapist (SLT).AIM: The aim of …
Determining Optimal Talker Variability for Nonnative Speech Training: A Systematic Review and Bayesian Network Meta-Analysis
J Speech Lang Hear Res. 2025 Mar 5;68(3):1006-1023. doi: 10.1044/2024_JSLHR-24-00599. Epub 2025 Feb 12.ABSTRACTPURPOSE: This meta-analysis study aimed to determine the optimal level of talker variability in training to maximize second-language speech learning.METHOD: We conducted a systematic search for studies comparing different levels of talker variability in nonnative speech training, …
Impact of Modified Diet, Swallowing Exercises, and Neuromuscular Electrostimulation on Severity of Oropharyngeal Dysphagia of Geriatric Patients
Medicina (Kaunas). 2024 Nov 23;60(12):1927. doi: 10.3390/medicina60121927.ABSTRACTBackground and Objectives: Oropharyngeal dysphagia is a common swallowing disorder, characterized by difficulties in moving food and liquids from the mouth to the esophagus; it is particularly prevalent among older adults with neurological conditions. This study aimed to evaluate the effectiveness of a short-term complex …
Prevalence of Oropharyngeal Dysphagia in Patients With Advanced Cognitive Impairment
Alzheimers Dement. 2025 Jan 9;20(Suppl 5):e093170. doi: 10.1002/alz.093170. eCollection 2024 Dec.ABSTRACTINTRODUCTION: Patients with severe cognitive impairment, with the progression of the disease, show behavioral impairments, loss of functionality and, in many cases, swallowing changes (dysphagia). Dysphagia comes with serious complications that can cause health damage, such as malnutrition, dehydration and serious …
Prevalence and Risk Factors of Oropharyngeal Dysphagia in Newly Diagnosed Head-and-Neck Cancer Patients
Cancers (Basel). 2024 Dec 24;17(1):9. doi: 10.3390/cancers17010009.ABSTRACTBACKGROUND: Head-and-neck cancer (HNC) can cause oropharyngeal dysphagia (OD). Early identification of OD in newly diagnosed HNC patients is important to better prepare patients for their cancer treatment trajectory. The aim of this study is (1) to assess the prevalence of OD in HNC patients within …
Effect of Thickened Fluids on Swallowing Function in Oropharyngeal Dysphagia: Impact of Shear Rheology and Disorder Subtype
Neurogastroenterol Motil. 2025 Jan 21:e15003. doi: 10.1111/nmo.15003. Online ahead of print.ABSTRACTINTRODUCTION: Fluid thickeners used in the management of oropharyngeal dysphagia exhibit non-Newtonian shear-thinning rheology, impacting their viscosity during deglutition. This study investigated how the rheological properties of thickened fluids affect pharyngeal swallowing parameters in patients with oropharyngeal motor disorders diagnosed …
Deficits in facial emotion recognition and cognitive function among baby boomers
Acta Psychol (Amst). 2025 Mar;253:104738. doi: 10.1016/j.actpsy.2025.104738. Epub 2025 Jan 22.ABSTRACTFacial emotion recognition (FER), a key component of social cognition, plays a critical role in social interactions. In the aging process, FER among older adults holds significant potential as a tool for diagnosing cognitive function or enhancing interpersonal relationships. However, research …
Sci Adv. 2025 Mar 7;11(10):eads1560. doi: 10.1126/sciadv.ads1560. Epub 2025 Mar 5.ABSTRACTCross-sectional age-skill profiles suggest that cognitive skills start declining by age 30 if not earlier. If accurate, such age-driven skill losses pose a major threat to the human capital of societies with rapidly aging populations. We estimate actual age-skill profiles from individual …
Empathy is associated with older adults' social behaviors and verbal emotional expressions throughout the day
Sci Rep. 2025 Jan 2;15(1):269. doi: 10.1038/s41598-024-82550-0.ABSTRACTEmpathy plays a crucial role in promoting older adults' interpersonal experiences, but it remains unclear how these benefits of empathy occur. To address this gap, we examined associations between empathy and how older adults behave and express emotions during their daily interpersonal …
Disparities in mortality outcomes among older adults with communication disabilities using the National Health and Aging Trends Study
Arch Phys Med Rehabil. 2024 Dec 21:S0003-9993(24)01410-2. doi: 10.1016/j.apmr.2024.12.013. Online ahead of print.ABSTRACTOBJECTIVE: To examine if a nationally representative population of older adults with communication disabilities (CDs) have a higher risk of mortality when compared to older adults without these disabilities, independent of sociodemographic, health, and other …
Effects of a Steno Diabetes Dialogue Card-Based Intervention on Self-Perceived Health, Health Literacy, and Glycemic Control in Older Adults With Type 2 Diabetes Mellitus Living in the Community
Hu Li Za Zhi. 2025 Feb;72(1):64-75. doi: 10.6224/JN.202502_72(1).09.ABSTRACTBACKGROUND: The process of aging is associated with the deterioration of normal body functions as well as lower health awareness due to a reduced ability to acquire and understand health-related information. The subjects of this study were older adults with diabetes mellitus …
Perceptual adaptation to dysarthric speech is modulated by concurrent phonological processing: A dual task study
J Acoust Soc Am. 2025 Mar 1;157(3):1598-1611. doi: 10.1121/10.0035883.ABSTRACTListeners can adapt to noise-vocoded speech under divided attention using a dual task design [Wang, Chen, Yan, McGettigan, Rosen, and Adank, Trends Hear. 27, 23312165231192297 (2023)]. Adaptation to noise-vocoded speech, an artificial degradation, was largely unaffected for domain-general (visuomotor) and domain-specific (semantic or phonological) dual tasks. …
Is there a decline in speech and swallowing in Amyotrophic Lateral Sclerosis over ten years?
Codas. 2025 Feb 10;37(2):e20240159. doi: 10.1590/2317-1782/e20240159pt. eCollection 2025.ABSTRACTPURPOSE: To analyze the evolution of speech and swallowing decline in patients with amyotrophic lateral sclerosis (ALS) over a ten-year period.METHODS: A retrospective and longitudinal cohort study. Data were collected using the Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS-R) from 101 medical …
J Oncol Pharm Pract. 2025 Feb 28:10781552251324868. doi: 10.1177/10781552251324868. Online ahead of print.ABSTRACTBACKGROUND: Irinotecan is chemotherapeutic agent often used in abdominal cancers such as colorectal and pancreatic cancers. While often associated with non-central nervous system (CNS) adverse effects, in rare cases it may present with paresthesias and dysarthrias. In one case, a …
Associations Between Non-Verbal Cognitive Assessment and Stroke Recovery via Screening Test for Aphasia and Dysarthria
J Stroke Cerebrovasc Dis. 2024 Dec 28:108217. doi: 10.1016/j.jstrokecerebrovasdis.2024.108217. Online ahead of print.ABSTRACTOBJECTIVE: Non-verbal Screening Test for Aphasia and Dysarthria scores correlate with post-stroke cognitive function; however, their correlations with activities of daily living dependency and home discharge (cognitive function-associated outcomes) remain unclear. We investigated the correlation of these scores …
Auteurs québécois: Joël Macoir, Monica Lavoie et Laura Monetta
dCALQ - a new screening test for the acquired deficits of number processing: Development and normative data
Appl Neuropsychol Adult. 2025 Feb 11:1-10. doi: 10.1080/23279095.2025.2464065. Online ahead of print.ABSTRACTThe clinical management of number processing disorders is often overlooked, partly due to the lack of standardized assessment tools specifically designed for acalculia. For French-speaking clinicians and researchers, there is currently no assessment battery grounded in theoretical models of cognitive …
Quebec French Version of the Hayling Sentence Completion Test: Error Scoring Guidelines, Normative Data for Adults and the Elderly and Validation Study in Mild Cognitive Impairment and Alzheimer's Disease
Arch Clin Neuropsychol. 2025 Feb 20:acaf014. doi: 10.1093/arclin/acaf014. Online ahead of print.ABSTRACTINTRODUCTION: Deficits in inhibition have been associated with various clinical conditions, including neurodegenerative diseases. The Hayling Sentence Completion Test (HSCT) is an assessment tool commonly used in clinical settings to measure verbal initiation and prepotent verbal response inhibition. …
