Félicitations à nos chercheurs et à nos chercheurs-cliniciens pour leurs publications !
Plusieurs membres de l’IHOT
Cohen S, Labopin M, Bambace N, Ahmad I, Dumont-Lagacé M, Ciceri F, McLornan DP, Labussière-Wallet H, Kröger N, Peffault de Latour R, Chalandon Y, Forcade E, Cluzeau T, Jindra P, Kulagin A, Roy J, Lachance S, Barabé F, Caudrelier P, Sauvageau G, Yakoub-Agha I, Mohty M. Comparison of Outcomes after UM171-Expanded Cord Blood and Six Conventional Donor Source Transplants: A Matched Analysis from the EBMT Registry. Transplant Cell Ther. 2025 Aug 14:S2666-6367(25)01365-X. doi: 10.1016/j.jtct.2025.08.006. Online ahead of print. PMID: 40818826.
Laflamme R, Lisi V, Hébert J, Sauvageau G, Lemieux S, Lavallée VP, Lettre G. Replication of a GWAS signal near HLA-DQA2 with AML using a disease-only cohort and external population-based controls. PMID: 40518289. Blood Neoplasia. 2025 May 19;2(3):100118. doi: 10.1016/j.bneo.2025.100118. eCollection 2025 Aug. PMID: 40746938.
Prof. Karine Bilodeau
Bilodeau K, Torabi P, Gélinas-Gagné C, Vinette B, Rousseau P, Hartono B, Tamaro L, Fernandez N. Bridging gaps in cancer care for young adults: A collaborative e-learning initiative for oncology nurses. Can Oncol Nurs J. 2025 May 1;35(3):496-517. doi: 10.5737/23688076353496. eCollection 2025. PMID: 40873749.
Bilodeau K, Henriksen C, Aloisio Alves C, Torabi P, Piché L, Pepin J, Lee V, Vachon MF, Folch N, Pomey MP, Fernandez N. Learning to Live with and Beyond Hematological Cancer: A Narrative Study for a Comprehensive Patient Perspective. Semin Oncol Nurs. 2025 Jul 24:151952. doi: 10.1016/j.soncn.2025.151952. Online ahead of print. PMID: 40713261.
Guiouillier P, Jouteau S, Bilodeau K, Roquelaure Y, Porro B. Work Participation of Patients Affected by Advanced Cancer: A Scoping Review of Current Knowledge. European Journal of Cancer Care, Volume 2025, Article ID 5333340, 22 July 2025, https://doi.org/10.1155/ecc/5333340.
Dr Lambert Busque
Koschmieder S, Schulte C, von der Heyde E, Busque L, Boyer-Perrard F, Devos T, Passamonti F, Cheng WY, Cheng M, Nuortti M, Baum V, Harrison C. Clinical outcomes of high-risk patients with polycythemia vera after suboptimal response to first-line therapy who switched to ruxolitinib versus nonswitchers: results from the PV-Switch study. Ther Adv Hematol. 2025 Jul 4:16:20406207251342199. doi: 10.1177/20406207251342199. eCollection 2025. PMID: 40620727.
Dr Jean-Sébastien Claveau
Claveau JS, Kapoor P, Binder M, Buadi F, Dingli D, Dispenzieri A, Fonder A, Gertz M, Gonsalves W, Hayman S, Hobbs M, Hwa Christenson YL, Kourelis T, Lacy M, Leung N, Lin Y, Warsame R, Kyle R, Rajkumar SV, Kumar SK. Eliminating the need for sequential confirmation of response in multiple myeloma. Blood. 2025 Aug 14;146(7):802-805. doi: 10.1182/blood.2024027949. PMID: 40489635.
Dre Sandra Cohen
Roskes ML, Martinez-Fundichely A, Cohen S, Balaban M, Khuan Wong C, Li W, Gonzalez TA, Tehim AB, Xu H, ElNaggar S, Myers M, Bareja R, Dorsaint P, Gorski K, Asad M, Al Assaad M, Robinson BD, Sigouros M, Barnett E, Manohar J, Tagawa S, Nanus D, Molina A, Nauseef JT, Sternberg CN, Mosquera JM, Scher HI, Sboner A, Raphael BJ, Chen Y, Khurana E. Genomic alterations in the YAP/TAZ pathway are associated with stem cell-like castration-resistant prostate cancer. medRxiv [Preprint]. 2025 Jul 2:2025.07.01.25330467. doi: 10.1101/2025.07.01.25330467. PMID: 40630580.
Dr Jean-Sébastien Delisle
Cochran-Perez MR, Sharma P, Delisle JS, Schlesinger M, Rao H, Trias J, Keller M. Bispecific antibody therapy-associated opportunistic infections: cytomegalovirus retinitis and chronic salmonellosis in a non-HIV patient. Haematologica. 2025 Jul 17. doi: 10.3324/haematol.2025.287351. Online ahead of print. PMID: 40671496.
Delisle JS, Fournier D, Santerre K, Rochette S, Zawati MH, Dumont-Lagacé M, Turcotte S, Guertin JR, Vermette P, Tremblay JP, Parisotto M, Beauséjour C, Petropoulos L, Kekre N, Michaud S, Dieudé M. Harnessing the promises of cell therapy, gene therapy, and regenerative medicine in Québec, Canada. Front Med (Lausanne). 2025 Jun 3:12:1581058. doi: 10.3389/fmed.2025.1581058. eCollection 2025. PMID: 40529124.
Porcheron C, Le Devehat M, Roubtsova A, Bayat H, Evagelidis A, Jafarzadeh L, Sachan V, Labrecque N, Fonta Holder A, Susan-Resiga D, Essalmani R, Boudreau G, Prat A, Cusseddu R, Côté JF, Khatib AM, Delisle JS, Seidah NG. Blockade of colon cancer metastasis via single and double silencing of PCSK7/ PCSK9: enhanced T cells cytotoxicity in mouse and human. J Immunother Cancer. 2025 Jun 15;13(6):e011364. doi: 10.1136/jitc-2024-011364. PMID: 40518289.
Dre Caroline Lamarche
Valentini N, Requejo Cier CJ, Lamarche C. Highlights of 2024: Tregs immunometabolism and how to counter inflammatory niches. Immunol Cell Biol. 2025 Jul;103(6):504-508. doi: 10.1111/imcb.70027. Epub 2025 May 4. PMID: 40320285.
Dr Richard LeBlanc
Ailawadhi S, Ĺ piÄŤka I, Spencer A, Lu J, Oriol A, Ling S, Schjesvold F, Berkovits A, Hus M, Li C, Dimopoulos MA, Rajnics P, KalayoÄźlu Beşışık SK, Hungria V, Del Rosario Custidiano M, Parmar G, Leleu X, Li F, Cerchione C, Gomez C, Ishida T, Mateos MV, Buck TT, LeBlanc R, MinaĹ™Ăk J, Goldschmidt H, Zhang R, SĂ©miond D, Suzan F, Stefanova-Urena MS, Koch V, Moreau P. Erratum: Isatuximab Subcutaneous by On-Body Injector Versus Isatuximab Intravenous Plus Pomalidomide and Dexamethasone in Relapsed/Refractory Multiple Myeloma: Phase III IRAKLIA Study. J Clin Oncol. 2025 Aug 8:JCO2501767. doi: 10.1200/JCO-25-01767. Online ahead of print. PMID: 40779730.
Prof. Sylvie Lesage
Laplante V, Rousseau M, Pasquin S, Bourel C, Uriarte M, Affar EB, Najmanovich R, Lesage S, Gauchat JF. CLCF1 promotes IL12Rβ2 proteolysis and limits Th1 differentiation. Cytokine. 2025 Oct:194:156989. doi: 10.1016/j.cyto.2025.156989. Epub 2025 Jul 7. PMID: 40628045.
Fois A, DeschĂŞnes S, Bourel C, Beauchamp C, Lombard-Vadnais F, Ruiz M, Charron G, Coderre L; LSFC Consortium; Rioux JD, Lesage S. Disruption of Lrpprc affects B cell development and proliferation in a mouse model of Leigh Syndrome French Canadian type. J Rare Dis (Berlin). 2025;4(1):31. doi: 10.1007/s44162-025-00094-x. Epub 2025 Jul 1. PMID: 40607235.
Rioux JD, Boucher G, Forest A, Bouchard B, Coderre L, Daneault C, Robillard Frayne I, Thompson Legault J, Bitton A, Ananthakrishnan A, Lesage S, Xavier RJ, Des Rosiers C; iGenoMed Consortium. Serum proteomic and metabolomic analyses from patients with IBD identify biological pathways associated with treatment success with anti-integrin therapy. Immunol Cell Biol. 2025 Aug;103(7):648-663. doi: 10.1111/imcb.70039. Epub 2025 Jun 12. PMID: 40509637.
Prof. Christopher Rudd
Oroya A, Rudd CE. CD4/CD8-p56lck Induced T-Cell Receptor Signaling and Its Implications for Immunotherapy. Biomolecules. 2025 Jul 29;15(8):1096. doi: 10.3390/biom15081096. PMID: 40867541.
Wang H, Moon EY, Azouz A, Wu X, Smith A, Schneider H, Hogg N, Rudd CE. Author Correction: SKAP-55 regulates integrin adhesion and formation of T cell-APC conjugates. Nat Immunol. 2025 Aug;26(8):1423. doi: 10.1038/s41590-025-02239-y. PMID: 40629128.
Moës B, Krueger J, Kazanova A, Liu C, Gao Y, Ponnoor NA, Castoun-Puckett L, Oroya Lazo AC, Huong L, Cabald AL, Hien Tu T, Rudd CE. GSK-3 regulates CD4-CD8 cooperation needed to generate super-armed CD8+ cytolytic T cells against tumors. bioRxiv [Preprint]. 2025 Apr 9:2025.03.08.642085. doi: 10.1101/2025.03.08.642085. PMID: 40161618.
Dre Natasha Szuber
Tefferi A, Loscocco GG, Rokach L, Tadmor T, Faldu P, Melamed G, Alapi H, Abdelmagid M, Abdelaziz RM, Yousuf M, Nakhleh M, Pardanani A, Begna KH, Patnaik MM, Szuber N, Carobbio A, Barbui T, Reichard KK, He R, Guglielmelli P, Gangat N, Vannucchi AM. Triple A Plus (AAA+) Survival Prediction Model for Essential Thrombocythemia: Analysis Involving 7308 Patients. Am J Hematol. 2025 Sep 3. doi: 10.1002/ajh.70065. Online ahead of print. PMID: 40899793.
Bolarinwa A, Szuber N, He R, Pardanani A, Gangat N, Tefferi A. CSF3R mutations and variants in myeloid neoplasms: associated phenotypes, co-mutations, and survival trends. Haematologica. 2025 Jul 10. doi: 10.3324/haematol.2025.288026. Online ahead of print. PMID: 40637773.